C-Reactive Protein (CRP) Serum Whole Blood Rapid Test (Cassette)

Diagnostic Automation offers a C-Reactive Protein (CRP) Serum/Whole Blood Rapid Test (Cassette) RapiCard Insta Test which is a one-step immunochromatography based test for diagnostic. This CRP Serum/Whole Blood Rapid Test is designed for semi-quantitative determination of CRP in human serum or whole blood specimens. The sensitivity of the CRP Rapid Test can semi-quantitatively detect CRP in serum or whole blood at: < 5 ug / mL, 5-10 ug/mL and > 10 ug/mL ranges.

Materials Provided with CRP Rapid Test kit:
1. CRP Rapid Test device
2. Sample buffer

Materials required but not provided:
1. Serum collection containers.
2. Timer or Clock

CRP Rapid Test kit Background Information

CPR is composed of five protein subunits, produced by the liver and found in blood that plays a key role in the innate immune response. Strong evidence indicates that patients with elevated basal levels of CRP are at an increased risk of hypertension, heart diseases, and diabetes. CRP is proposed as a screening test for predicting risk and guiding preventive approaches in cardiac diseases Normal concentration in healthy human serum is usually lower than 10 mg/L, slightly increasing with aging. Higher levels are found in late pregnant women, mild inflammation and viral infections (10-40 mg/L), active inflammation, bacterial infection (40-200 mg/L), severe bacterial infections and burns (>200 mg/L). The half-life of CRP is constant, thus, CRP level is mainly determined by the rate of its production. A level above 2.4 mg/L has been associated with a doubled risk of a coronary event compared to levels below 1 mg/L. Inflammation can play an important role in atherosclerosis, the process in which fatty deposits build up in coronary arteries. Interest in CRP originated when studies found that patients with unstable angina or chest pain had high levels of this marker. Researchers found that CRP could be used to predict who would go on to have a heart attack. Moreover, in a meta-analysis of 20 studies involving 1,466 patients with coronary artery disease, CRP levels were found to be reduced after exercise interventions. Among those studies, higher CRP concentrations or poorer lipid profiles before beginning exercise were associated with greater reductions in CRP. Other studies have shown that CRP is not a predictor of heart attack risk in people without symptoms of heart disease.

CRP Rapid Test Principle

This CRP Serum/Whole Blood Rapid Test is based on the principle of specific immunochemical reaction between antibodies and antigens to analyze particular compounds in human serum specimen. The CRP Rapid Test relies on the competition for binding antibody between CRP-dye conjugate and free CRP which may be present in the specimen being tested. Specimen collection and preparation instructions are easy to follow. The CRP Rapid Test is safe, accurate, and quick. The range of CRP concentration in serum or whole blood can be detected in 10 minutes. See product insert for more details

Product Details