Monoclonal Mouse Antibody to Human
Cyclin E Protein 
F, P/H

Catalog No.: Mob 266 Concentrated 1ml
Mob 266-05 Concentrated 0.5ml
PDM 145 Prediluted 6ml

Immunogen: Synthetic peptide corresponding to human cyclin E protein.
Clone: HE12
Isotype: IgG1
Positive Control: Breast carcinoma
Cellular Localization: Nuclear
Specificity: This antibody recognizes a doublet of 50 kDa and a single band of 42 kDa identified as cyclin E. Cyclin proteins are a family of related proteins, which control the progression of the eukaryotic cell cycle. Overexpression of cyclin E shortens the length of the G1 phase, accelerating progression of S phase. The activity of cyclin E is mediated through its activation of cyclin dependent kinase 2 (cdk2) protein and is modulated by the presence of tumor suppressor proteins such as p16.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

For more information please visit the DBS website at dbiosys.com

Additional Information