Monoclonal Mouse Antibody to
O(6)-Methylguanine-DNA-Methyltransferase (MGMT) 
F, P/H

Catalog No.: Mob 423 Concentrated 1ml
Mob 42-053 Concentrated 0.5ml

Immunogen: Recombinant human MGMT protein.
Clone: MT3.1
Isotype: IgG1
Positive Control: Tonsil
Cellular Localization: Nuclear and cytoplasmic
Specificity: O(6)-methylguanine-DNA-methyltransferase (MGMT) is a 22 kDa human DNA repair protein that removes O(6)-alkylguanine DNA adducts. MGMT acts as a suicide acceptor protein repairing the DNA by accepting alkyl groups and consequently inactivating itself. This antibody stains all mantle zone lymphocytes and 50% of germinal center lymphocytes. Basaloid epithelial cells of tonsil squamous mucosa are also stained positive with this antibody.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

For more information please visit the DBS website at dbiosys.com

Additional Information