Monoclonal Mouse Antibody to Human
Retinoblastoma Gene Protein (Rb)
F, P/H

Catalog No.: Mob 220 Concentrated 1ml
Mob 220-05 Concentrated 0.5ml
PDM 111 Prediluted 6ml

Immunogen: Recombinant human Rb protein.
Clone: 1F8
Isotype: IgG1, kappa
Positive Control: Colon carcinoma
Cellular Localization: Nuclear
Specificity: This antibody recognizes human retinoblastoma gene protein. Rb gene, a prototype of tumor suppressor genes, has been associated with development
and/or progression of bladder cancer as well as sarcoma and small cell lung cancer. Functional Rb gene loss has been reported to occur in bladder cancer and osteosarcoma. A significantly poorer tumor-free survival rate was noted for those patients who had a tumor with an altered Rb protein with or without vascular invasion.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

For more information please visit the DBS website at dbiosys.com

Additional Information