Monoclonal Mouse Antibody to
Thyroid Peroxidase 
F, P/H

Catalog No.: Mob 418 Concentrated 1ml
Mob 418-05 Concentrated 0.5ml

Immunogen: Human thyroid peroxidase (hTPO) purified from thyroid microsomes by immunoaffinity chromatography.
Clone: MoAb47
Isotype: IgG1
Positive Control: Thyroid
Cellular Localization: Cytoplasmic
Specificity: Thyroid peroxidase (TPO) is a transmembrane protein of 107kDa containing a heme prosthetic group. It is present as a dimer on the apical surface of thyroid follicular cells. TPO is the primary enzyme involved in thyroid hormone synthesis. Malignant thyroid tumors exhibit an anomaly in TPO resulting in lower affinity for anti-TPO. This antibody may aid in the differentiation between benign and malignant thyroid tumors.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

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Additional Information