Monoclonal Mouse Antibody to Human
Cyclin E Protein 
F, P/H

Catalog No.: Mob 181 Concentrated 1ml
Mob 181-05 Concentrated 0.5ml
Immunogen: Synthetic peptide corresponding to the full length cyclin E molecule.
Clone: 13A3
Isotype: IgG2a, kappa
Positive Control: Breast carcinoma
Cellular Localization: Nuclear
Specificity: Cyclin proteins are a family of related proteins, which control the progression of the eukaryotic cell cycle. Overexpression of cyclin E shortens the length of the G1 phase, accelerating progression of S phase. The activity of cyclin E is mediated through its activation of cyclin dependent kinase 2 (cdk2) protein and is modulated by the presence of tumor suppressor proteins such as p16.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

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Additional Information