Monoclonal Mouse Antibody to
Paxillin 
F, P/H

Catalog No.: Mob 385 Concentrated 1ml
Mob 385-05 Concentrated 0.5ml

Immunogen: BALB/C mice were immunized with purified full-length recombinant human paxillin protein.
Clone: 5H11
Isotype: IgG1, kappa
Positive Control: Colon carcinoma
Cellular Localization: Cell membrane, cytoplasmic
Specificity: This antibody binds to a protein of 68 kDa. Paxillin is a focal adhesion protein and a substrate for several tyrosine kinases such as src, FAK and p210 bcr/ abl. The tyrosine phosphorylation of paxillin is affected by conditions that change cell-cell adhesion. Although paxillin was initially discovered in fibroblasts, its phosphorylation may also be important during neurite extension during differentiation. This antibody cross-reacts with rat.

F=Frozen P=Formalin Fixed Paraffin Embedded H=Heat Induced Pretreatment E=Enzyme Pretreatment

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Additional Information